Liver-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice
A. K. Singh, B. Chaube, A. Canfran-Duque, X. Zhang, N. L. Price, B. Aryal, J. Sun, K. M. Citrin, N. Rotllan, R. Lee, Y. Suarez, C. Fernandez-Hernando
This study shows that liver-specific ANGPTL4 suppression improves obesity-related diabetes and reduces atherosclerosis in mice by enhancing lipid metabolism and reducing inflammation.
bioRxiv · Jun 2, 2020Physiology