Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
D. Joshi, B. G. Coon, R. Chakraborty, H. Deng, P. Fernandez Tussy, E. Meredith, J. G. Traylor, A. W. Orr, C. Fernandez-Hernando, M. A. Schwartz
This study identifies Pcdhg as a suppressor of Klf2/4 in endothelial cells, promoting atherosclerosis by inhibiting the Notch pathway.
bioRxiv · Jan 16, 2024 · PreprintCell Biology
S. Relovska, H. Wang, X. Zhang, P. Fernandez-Tussy, K. Jeong, J. Choi, Y. Suarez, J. McDonald, C. Fernandez-Hernando, J.-J. Chung
bioRxiv · Dec 21, 2023 · PreprintCell Biology
S. P. Srivastava, H. Zhou, R. Shenoi, M. Morris, L. Goedeke, B. K. Rajendran, O. Setia, B. Aryal, K. Kanasaki, D. Koya, A. Dardik, T. Bell, C. Fernandez-Hernando, G. Shulman, J. E. Goodwin
This study identifies Angptl4 as a fibrogenic molecule in diabetic kidney disease and shows that targeting its expression in kidneys reduces fibrosis and proteinuria.
bioRxiv · Nov 8, 2023Cell Biology
B. Qiu, A. Lawan, C. E. Xirouchaki, J.-S. Yi, M. Robert, L. Zhang, W. Brown, C. Fernandez-Hernando, X. Yang, A. M. Bennett
This study shows MKP1 suppresses AMPK activity via LKB1 nuclear retention, promoting NASH by inducing hepatocyte death and inflammation.
bioRxiv · Jul 10, 2023Physiology
P. FERNANDEZ TUSSY, J. Sun, M. P. Cardelo, N. L. Price, L. Goedeke, C. E. Xirouchaki, X. Yang, O. Pastor-Rojo, A. M. Bennett, T. Tiganis, Y. Suarez, C. Fernandez-Hernando
This study shows that deleting miR-33 in hepatocytes reduces NAFLD progression to NASH, fibrosis, and HCC by improving lipid metabolism and mitochondrial function.
bioRxiv · Jan 18, 2023 · PreprintPhysiology
I. Kabir, X. Zhang, J. Dave, R. Chakraborty, R. Qu, R. R. Chandran, A. Ntokou, E. Gallardo-Vara, B. Aryal, N. Rotllan, R. Garcia-Milian, J. Hwa, Y. Klugar, K. A. Martin, C. Fernandez-Hernando, D. M. Greif
This study shows that aged bone marrow-derived cells increase smooth muscle cell polyclonality in atherosclerotic plaques through reduced TET2 and increased TNF signaling.
bioRxiv · Jan 18, 2022Cell Biology
S. Ryu, I. Shchukina, Y.-H. Youm, H. Qing, B. K. Hilliard, T. Dlugos, X. Zhang, Y. Yasumoto, C. J. Booth, C. Fernandez-Hernando, Y. Suarez, K. M. Khanna, T. Horvath, M. O. Dietrich, M. Artyomov, , V. D. Dixit
This study shows that a ketogenic diet reduces inflammation and improves outcomes in aged mice infected with a coronavirus, suggesting potential therapeutic benefits for elderly COVID-19 patients.
bioRxiv · Sep 11, 2020 · PreprintImmunology
S. P. Srivastava, H. Zhou, O. Setia, A. Dardik, C. Fernandez-Hernando, J. Goodwin
This study shows that loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy by promoting fibrosis through Wnt signaling and EndMT/EMT mechanisms.
bioRxiv · Jun 29, 2020Cell Biology
A. K. Singh, B. Chaube, A. Canfran-Duque, X. Zhang, N. L. Price, B. Aryal, J. Sun, K. M. Citrin, N. Rotllan, R. Lee, Y. Suarez, C. Fernandez-Hernando
This study shows that liver-specific ANGPTL4 suppression improves obesity-related diabetes and reduces atherosclerosis in mice by enhancing lipid metabolism and reducing inflammation.
bioRxiv · Jun 2, 2020Physiology