Author

B. D. Needham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

R. Knight· 2 shared S. K. Mazmanian· 2 shared A. Fasano· 1 shared A. Kovtun· 1 shared A. Noto· 1 shared A. S. Campbell· 1 shared B. Carpenter· 1 shared D. Frank· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

R. Knight

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Author profile →

3 papers

Recent·Most cited

The microbiome shapes immunity in a sex-specific manner in mouse models of Alzheimer's disease

J. W. Bostick, T. J. Connerly, T. Thron, B. D. Needham, M. de Castro Fonseca, R. Kaddurah-Daouk, R. Knight, S. K. Mazmanian

This study shows that the microbiome influences immune responses and cognitive deficits in sex-specific ways in mouse models of Alzheimer's disease.

bioRxiv · May 7, 2024 · PreprintMicrobiology

Multi-omic analysis along the gut-brain axis points to a functional architecture of autism

J. T. Morton, D.-m. Jin, R. Mills, Y. Shao, G. Rahman, D. McDonald, K. Harold-Berding, B. D. Needham, M. F. Zurita, M. David, O. Averina, A. Kovtun, A. Noto, M. Mussap, M. Wang, , G. Taroncher-Oldenburg

The paper identifies a functional architecture of autism along the gut-brain axis using multi-omic data, revealing microbial and metabolic profiles linked to autism symptoms.

bioRxiv · Feb 25, 2022 · PreprintMicrobiology

Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder

B. D. Needham, M. D. Adame, G. Serena, D. R. Rose, G. M. Preston, M. C. Conrad, A. S. Campbell, D. H. Donabedian, A. Fasano, P. Ashwood, S. K. Mazmanian

The paper analyzes plasma and fecal metabolite profiles in children with ASD and typically developing controls to identify metabolic differences and their associations with clinical behaviors and GI dysfunction.

bioRxiv · May 17, 2020Biochemistry