Author

A. Noto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

A. Franchitto· 2 shared G. Pantaleo· 2 shared P. Pichierri· 2 shared A. Chassiakos· 1 shared A. Folgori· 1 shared A. Kovtun· 1 shared A. Lahm· 1 shared A. Leuzzi· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

A. Franchitto

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES

A. Noto, P. Valenzisi, F. Fratini, T. Kulikowicz, J. A. Sommers, F. Di Feo, V. Palermo, M. Semproni, M. Crescenzi, R. M. Brosh, A. Franchitto, P. Pichierri

This study shows that phosphorylation-dependent WRN-RPA interaction is essential for replication fork recovery after stalling at secondary DNA structures, preventing DNA damage and G4 accumulation.

bioRxiv · Aug 8, 2023 · PreprintCell Biology

Phosphorylation Status Of MUS81 Is A Modifier Of Olaparib Sensitivity In BRCA2-Deficient Cells

F. Blandino, E. Malacaria, C. Figlioli, A. Noto, G. M. Pugliese, A. Franchitto, P. Pichierri

This study shows that phosphorylation status of MUS81 affects PARPi sensitivity in BRCA2-deficient cells by modulating MUS81 activity in different phases of the cell cycle.

bioRxiv · Aug 13, 2022Cell Biology

Multi-omic analysis along the gut-brain axis points to a functional architecture of autism

J. T. Morton, D.-m. Jin, R. Mills, Y. Shao, G. Rahman, D. McDonald, K. Harold-Berding, B. D. Needham, M. F. Zurita, M. David, O. Averina, A. Kovtun, A. Noto, M. Mussap, M. Wang, , G. Taroncher-Oldenburg

The paper identifies a functional architecture of autism along the gut-brain axis using multi-omic data, revealing microbial and metabolic profiles linked to autism symptoms.

bioRxiv · Feb 25, 2022 · PreprintMicrobiology

Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19

A. Vitelli, S. Capone, A. Raggioli, M. Gentile, S. Battella, A. Lahm, A. Sommella, A. M. Contino, R. A. Urbanowicz, R. Scala, F. Barra, A. Leuzzi, E. Lilli, G. Miselli, A. Noto, , S. Colloca

This paper evaluates a gorilla adenovirus vaccine candidate for COVID-19, showing it is immunogenic in mice and macaques and supports its advancement to a Phase I clinical trial.

bioRxiv · Oct 22, 2020Immunology

Human follicular CD4 T cell function is defined by specific molecular, positional and TCR dynamic signatures.

K. Padhan, E. Moysi, A. Noto, A. Chassiakos, K. Ghneim, S. Shah, V. Papaioannou, G. Fabozzi, D. Ambrozak, A. Poultsidi, M. Ioannou, C. Fenwik, S. Darko, D. C. Douek, R.-P. Sekaly, , C. Petrovas

bioRxiv · May 12, 2020 · PreprintImmunology

CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals

A. Noto, F. Procopio, R. Banga, M. Suffiotti, J.-M. Corpataux, M. Cavassini, C. Fenwick, R. Gottardo, M. Perreau, G. Pantaleo

This study identifies CD32+ CD4 T cells in lymph nodes as a population with persistent HIV-1 transcription, with CD32+PD-1+ cells showing the highest levels in both viremic and treated individuals.

bioRxiv · May 24, 2018Immunology