Author

B. Druker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Koren· 1 shared B. Chang· 1 shared C. E. Tognon· 1 shared C. Hammond· 1 shared C. J. Eaves· 1 shared C. Trevilla-Garcia· 1 shared D. Bottomly· 1 shared D. J. H. F. Knapp· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Koren

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2 papers

Recent·Most cited

A noncanonical FLT3 gatekeeper mutation disrupts gilteritinib binding and confers resistance

S. K. Joshi, S. Sharzehi, J. Pittsenbarger, D. Bottomly, C. E. Tognon, S. McWeeney, B. Druker, E. Traer

This study identifies a novel FLT3 mutation, N701K, that confers resistance to gilteritinib by blocking its binding, and suggests switching to type 2 FLT3 inhibitors may be effective.

bioRxiv · Jan 27, 2021Cancer Biology

Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture

J. C. Rivera-Mulia, T. Sasaki, C. Trevilla-Garcia, N. Nakamichi, D. J. H. F. Knapp, C. Hammond, B. Chang, J. W. Tyner, M. Devidas, J. Zimmerman, K. Klein, V. Somasundaram, B. Druker, T. Gruber, A. Koren, , D. M. Gilbert

The paper compares DNA replication timing profiles of BCP-ALL leukemic samples with normal B-lineage differentiation stages to identify clinically relevant features.

bioRxiv · Apr 11, 2019 · PreprintCancer Biology