B. Chang

Cryopreservation and revival of Hawaiian stony corals via isochoric vitrification

This paper reports the first successful cryopreservation and revival of Hawaiian stony coral fragments using isochoric vitrification, demonstrating viability and a prototype pipeline for global coral conservation.

Horizontal transmission of penicillin binding protein 1A caused a nationwide spread of β-lactam resistance in pneumococci

The paper traces the nationwide spread of β-lactam resistance in pneumococci through horizontal transmission of a specific PBP1A variant, highlighting its role in resistance emergence.

A small-molecule lycorine derivative protects from obesity by targeting Na+/K+-ATPase α3 independent of food intake suppression

The paper identifies HLY72, a small-molecule derivative of lycorine, as an anti-obesity agent that targets Na+/K+-ATPase α3 in the brain, promoting lipolysis and thermogenesis without affecting food intake.

Simultaneous expression of UV and violet SWS1 opsins expands the visual palette in a group of freshwater snakes.

This study identifies two functionally distinct SWS1 opsins in Helicops snakes, enabling UV and violet vision, and links this to improved visual acuity and chromatic discrimination.

Synergistic Enzyme Mixtures to Realize Near-Complete Depolymerization in Biodegradable Polymer/Additive Blends

This study shows that synergistic enzyme mixtures can achieve near-complete depolymerization of polymer/additive blends by combining random chain scission and processive depolymerization.

Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates

This study evaluates mRNA-1273 vaccine efficacy against SARS-CoV-2 B.1.351 in nonhuman primates, finding that two doses significantly reduce viral replication in the airways.

The jasmine (Jasminum sambac) genome and flower fragrances

This study presents the first de novo genome of Jasminum sambac and identifies gene clusters and pathways involved in flower fragrance biosynthesis.

Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture

The paper compares DNA replication timing profiles of BCP-ALL leukemic samples with normal B-lineage differentiation stages to identify clinically relevant features.

Cone-like rhodopsin expressed in the all cone retina of the colubrid pine snake as a potential adaptation to diurnality

The study identifies blue-shifted rhodopsin with cone opsin properties in the all-cone retina of Pituophis melanoleucus, suggesting evolutionary transmutation from rod ancestors as an adaptation for diurnal vision.