Author

S. McWeeney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cancer & tumor microenvironment· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

S. Jeng· 3 shared D. Bottomly· 2 shared L. Gralinski· 2 shared M. T. Ferris· 2 shared M. T. Heise· 2 shared R. S. Baric· 2 shared V. D. Menachery· 2 shared A. B. Pinkerton· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

S. Jeng

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Author profile →

6 papers

Recent·Most cited

A noncanonical FLT3 gatekeeper mutation disrupts gilteritinib binding and confers resistance

S. K. Joshi, S. Sharzehi, J. Pittsenbarger, D. Bottomly, C. E. Tognon, S. McWeeney, B. Druker, E. Traer

This study identifies a novel FLT3 mutation, N701K, that confers resistance to gilteritinib by blocking its binding, and suggests switching to type 2 FLT3 inhibitors may be effective.

bioRxiv · Jan 27, 2021Cancer Biology

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

J. Graham, J. Swarts, S. R. Leist, A. Schafer, V. D. Menachery, L. Gralinski, S. Jeng, D. R. Miller, M. Mooney, S. McWeeney, M. T. Ferris, F. Pardo-Manuel de Villena, M. T. Heise, R. S. Baric, J. M. Lund

The paper shows that baseline T cell immune signatures in mice predict virologic and disease outcomes upon SARS-CoV infection.

bioRxiv · Sep 21, 2020Immunology

The serine-threonine kinase TAO3 promotes cancer invasion and tumor growth by facilitating trafficking of endosomes containing the invadopodia scaffold TKS5α

S. Iizuka, M. Quintavalle, J. Ceja Navarro, K. P. Gribbin, R. J. Ardecky, M. Abelman, C.-T. Ma, E. Sergienko, F.-Y. Zeng, I. Pass, G. Thomas, S. McWeeney, C. A. Hassig, A. B. Pinkerton, S. A. Courtneidge

bioRxiv · Feb 27, 2020Cancer Biology

Mucin 4 Protects Female Mice from Coronavirus Pathogenesis

J. A. Plante, K. Plante, L. Gralinski, A. Beall, M. T. Ferris, D. Bottomly, R. R. Green, S. McWeeney, M. T. Heise, R. S. Baric, V. D. Menachery

This study identifies Muc4 as a protective factor in female mice against SARS-CoV pathogenesis, showing sex-specific effects without altering viral titers.

bioRxiv · Feb 19, 2020 · PreprintMicrobiology

A distinct neutrophil population invades the central nervous system during pancreatic cancer

K. G. Burfeind, X. Zhu, M. A. Norgard, P. R. Levasseur, B. Olson, K. A. Michaelis, E. R. S. Torres, S. Jeng, S. McWeeney, J. Raber, D. L. Marks

This study identifies a novel neutrophil population invading the brain during pancreatic cancer, mediated by CCR2/CCL2 and P2RX7, leading to anorexia and muscle catabolism.

bioRxiv · Jun 3, 2019 · PreprintImmunology

Myeloid Lineage Enhancers Drive Oncogene Synergy in CEBPA/CSF3R Mutant Acute Myeloid Leukemia

T. P. Braun, M. Okhovat, C. Coblentz, S. A. Carratt, A. Foley, Z. Schonrock, K. Nevonen, B. Davis, B. Garcia, D. LaTocha, B. R. Weeder, M. R. Grzadkowski, J. C. Estabrook, H. G. Manning, K. Watanabe-Smith, , J. E. Maxson

The paper identifies mutation synergy between CSF3R and CEBPA in AML, showing their interaction at myeloid lineage enhancers and the requirement of CEBPA mutations as an initial event.

bioRxiv · May 15, 2019Cancer Biology