Author

D. M. Gilbert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Assay:Hi-C· 3 Organism:human· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

T. Sasaki· 3 shared C. Trevilla-Garcia· 2 shared J. C. Rivera-Mulia· 2 shared J. Zimmerman· 2 shared A. Dimond· 1 shared A. Koren· 1 shared A. Maiser· 1 shared A. S. Belmont· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

T. Sasaki

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Author profile →

4 papers

Recent·Most cited

Nucleolus and centromere TSA-Seq reveals variable localization of heterochromatin in different cell types

P. Kumar, O. Gholamalamdari, Y. Zhang, L. Zhang, A. Vertii, T. van Schaik, D. Peric-Hupkes, T. Sasaki, D. M. Gilbert, B. van Steensel, J. Ma, P. D. Kaufman, A. S. Belmont

The paper uses TSA-seq to map genomic regions near nucleoli and pericentric heterochromatin in human cell lines, revealing variable heterochromatin localization and complex nuclear organization.

bioRxiv · Oct 29, 2023Cell Biology

Cohesin depleted cells rebuild functional nuclear compartments after endomitosis

M. Cremer, K. Brandstetter, A. Maiser, S. S. Rao, V. Schmid, M. Guirao-Ortiz, N. Mitra, S. Mamberti, K. N. Klein, D. M. Gilbert, H. Leonhardt, M. C. Cardoso, E. Lieberman Aiden, H. Harz, T. Cremer

The paper shows cohesin-depleted cells undergo endomitosis and rebuild a multilobulated nucleus with functional compartments despite lacking cohesin.

bioRxiv · Sep 14, 2020Cell Biology

Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture

J. C. Rivera-Mulia, T. Sasaki, C. Trevilla-Garcia, N. Nakamichi, D. J. H. F. Knapp, C. Hammond, B. Chang, J. W. Tyner, M. Devidas, J. Zimmerman, K. Klein, V. Somasundaram, B. Druker, T. Gruber, A. Koren, , D. M. Gilbert

The paper compares DNA replication timing profiles of BCP-ALL leukemic samples with normal B-lineage differentiation stages to identify clinically relevant features.

bioRxiv · Apr 11, 2019 · PreprintCancer Biology

Allele-specific control of replication timing and genome organization during development

J. C. Rivera-Mulia, A. Dimond, D. Vera, C. Trevilla-Garcia, T. Sasaki, J. Zimmerman, C. Dupont, J. Gribnau, P. Fraser, D. M. Gilbert

This study identifies allele-specific replication timing and genome organization differences in hybrid mouse embryos and shows they diminish during differentiation.

bioRxiv · Nov 21, 2017Cell Biology