Cell BiologybioRxiv
Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro
M. Seirup, S. Sengupta, S. Swanson…·J. A. Thomson
This study identifies three phases of hepatocyte dedifferentiation in culture through RNA-seq and ATAC-seq, revealing rapid chromatin changes and fetal gene activation.
DOI 10.1016/j.ygeno.2022.110330