Heparins enhance C1 esterase inhibitor activity: a promising remedy for acute hereditary angioedema
Y. Zhou, A. Maljuf-Cruz, J. Dennis, E. Woroch, L. Hor, B. Hellbusch, E. Archuleta, L. Fornis, C. Garcia, S. Aerts, X. Bai, S. Bevers, E. P. Schmidt, M. Bates, R. Fugit, , E. Chan
This study shows low-molecular weight heparins enhance C1-INH activity in HAE patients and in vitro, suggesting they could be a cost-effective treatment for acute HAE.
bioRxiv · Feb 10, 2022 · PreprintPharmacology & Toxicology