Alpha-1-antitrypsin binds to the glucocorticoid receptor with biological significance in macrophages
X. Bai, A. Bai, M. Tomasicchio, J. Hagman, A. Buckle, A. Gupta, V. Kadiyala, S. Bevers, K. Serban, K. Kim, Z. Feng, K. Spiender, G. Hagen, L. B. Fornis, D. E. Griffith, , E. D. Chan
This study identifies AAT binding to the glucocorticoid receptor in macrophages, showing its role in anti-inflammatory and host-defense functions.
bioRxiv · Mar 11, 2022 · PreprintImmunology