BioengineeringbioRxivPreprint
Potency of CRISPR-Cas Antifungals Is Enhanced by Co-targeting DNA Repair and Growth Regulatory Machinery at the Genetic Level
B. J. Mendoza, X. Zheng, J. C. Clements…·C. Trinh
This paper demonstrates that co-targeting essential and DNA repair genes enhances CRISPR-Cas antifungal efficacy in yeast, outperforming single-target approaches.
DOI 10.1101/2023.07.11.548496