BiochemistrybioRxiv
Cell-free chromatin particles released from dying cells inflict mitochondrial damage and ROS production in living cells
G. V. Raghuram, B. K. Tripathy, K. Avadhani…·I. Mittra
The paper shows that cell-free chromatin particles from dying cells cause mtDNA damage and ROS production in healthy cells, suggesting they are key triggers for oxidative stress-related diseases.
DOI 10.1038/s41420-023-01728-z