BioengineeringbioRxivPreprint
Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial
S. Zhang, A. Deshpande, B. K. Verma…·A. S. Popel
The paper develops a spatial quantitative systems pharmacology model for virtual clinical trials in HCC, validated with spatial multi-omics data from a neoadjuvant immunotherapy trial.
DOI 10.1101/2023.08.11.553000