Author

B. Koo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. tenOever· 1 shared C. Cadena· 1 shared C.-H. Sun· 1 shared D. Lee· 1 shared D.-Y. Shin· 1 shared E. Kim· 1 shared H. Wang· 1 shared J. Byun· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

B. tenOever

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

AMLs harboring DNMT3A-destabilizing variants show increased intratumor DNA methylation heterogeneity at bivalent chromatin domains

D. Lee, B. Koo, S.-H. Kim, J. Byun, J. Hong, D.-Y. Shin, C.-H. Sun, J.-J. Song, J. Kim, S. Jaiswal, S.-s. Yoon, S. Kim, Y. Koh

This study shows that DNMT3A-destabilizing mutations in AML increase DNA methylation heterogeneity at bivalent chromatin domains, affecting leukemic stem cell-niche interactions and drug response.

bioRxiv · Feb 13, 2023 · PreprintCancer Biology

Stress granules are shock absorbers that prevent excessive innate immune responses to dsRNA

S. Hur, M. Paget, C. Cadena, S. Ahmad, H. Wang, T. Jordan, E. Kim, Q. Zhang, B. Koo, S. Lyons, P. Ivanov, B. tenOever, X. Mu

This study shows stress granules regulate immune responses to dsRNA by preventing excessive inflammation and viral replication.

bioRxiv · Apr 26, 2021Immunology