Author

B. Kronsteiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. Dunachie· 3 shared A. Clarke· 2 shared M. Ali· 2 shared Y. F. Yazicioglu· 2 shared A. E. Armitage· 1 shared A. E. Preston· 1 shared A. L. Smith· 1 shared A. Leber· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersImmunology

S. Dunachie

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Author profile →

5 papers

Recent·Most cited

Iron deficiency causes aspartate-sensitive metabolic and proliferative dysfunction in CD8+ T cells

M. R. Teh, N. Gudgeon, J. N. Frost, L. V. Sinclair, A. L. Smith, C. L. Millington, B. Kronsteiner, J. Roberts, B. P. Marzullo, A. E. Preston, J. Rehwinkel, T. A. Milne, D. A. Tennant, S. J. Dunachie, A. E. Armitage, , H. Drakesmith

This study shows iron deficiency impairs CD8+ T cell proliferation and metabolism by disrupting mitochondrial function, but exogenous aspartate can rescue this defect.

bioRxiv · Feb 1, 2024 · PreprintImmunology

Asparagine availability controls B cell homeostasis

Y. F. Yazicioglu, E. Marin, K. Bentkowska, H. Andrew, R. Mitchell, Z. Y. Wong, J. Fergusson, M. Borsa, J. C. Johnstone, M. Ali, B. Kronsteiner, I. L. Furlani, J. I. MacRae, M. J. Devine, M. Coles, , A. Clarke

The paper shows asparagine metabolism is critical for B cell function and germinal centre homeostasis, with Asn deprivation impairing survival, proliferation, and immune responses.

bioRxiv · Apr 3, 2023Immunology

A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus

M. Inthawong, N. Pinthong, A. Thaiprakhong, T. Wangrangsimakul, P. Sunyakumthorn, J. Hill, P. Sonthayanon, D. H. Paris, S. Dunachie, B. Kronsteiner

This study optimizes a whole blood intracellular cytokine assay to assess polyfunctional CD4+ T cell responses in acute scrub typhus, demonstrating its utility in field settings with limited resources.

bioRxiv · Oct 28, 2022Immunology

Dynamic mitochondrial transcription and translation in B cells control germinal centre entry and lymphomagenesis

Y. F. Yazicioglu, E. M. Marin, C. Sandhu, S. Galiani, I. G. A. Raza, M. Ali, B. Kronsteiner, E. Compeer, M. Attar, S. Dunachie, M. Dustin, A. Clarke

This study shows that mitochondrial transcription and translation in B cells are critical for germinal centre entry and lymphomagenesis, with TFAM playing a key role.

bioRxiv · Jul 19, 2022 · PreprintImmunology

Identification of regulatory genes through global gene expression analysis of a Helicobacter pylori co-culture system

R. Hontecillas, N. Tubau-Juni, J. Bassaganya-Riera, A. Leber, V. Zoccoli-Rodriguez, B. Kronsteiner, M. Viladomiu, V. Abedi

The paper identifies regulatory genes in a Helicobacter pylori co-culture system using transcriptomic analysis and experimental validation.

bioRxiv · Jan 17, 2019Immunology