Author

B. Lau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

H. Ji· 2 shared J. Mardia· 2 shared J. Neu· 2 shared K. Tatwawadi· 2 shared M. Kubit· 2 shared M. Wootters· 2 shared P. Griffin· 2 shared S. Chandak· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

H. Ji

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas

G. Batsios, S. Udutha, C. Taglang, A. M. Gillespie, B. Lau, S. Ji, T. Phoenix, S. Mueller, S. Venneti, C. Koschmann, P. Viswanath

This study shows imipridones induce GABA accumulation in diffuse midline gliomas, which can be used for non-invasive imaging and therapy.

bioRxiv · Jun 7, 2024 · PreprintCancer Biology

ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways

A. Rubina, M. Patel, K. Nightingale, M. Potts, C. A. Fielding, S. Kollnberger, B. Lau, K. Ladell, K. L. Miners, J. Nichols, L. Nobre, D. Roberts, T. M. Trinca, J. P. Twohig, V.-M. Vlahava, , E. C. Y. Wang

This paper identifies how HCMV targets ADAM17 to modulate surface proteins and immune pathways, revealing a novel viral immunomodulation strategy.

bioRxiv · Mar 16, 2023Microbiology

Overcoming high nanopore basecaller error rates for DNA storage via basecaller-decoder integration and convolutional codes

S. Chandak, J. Neu, K. Tatwawadi, J. Mardia, B. Lau, M. Kubit, R. Hulett, P. Griffin, M. Wootters, T. Weissman, H. Ji

The paper reduces nanopore DNA sequencing error rates by integrating a Viterbi decoder with a basecaller and using convolutional codes, achieving lower reading costs than existing methods.

bioRxiv · Dec 20, 2019 · PreprintBioengineering

Improved read/write cost tradeoff in DNA-based data storage using LDPC codes

S. Chandak, K. Tatwawadi, B. Lau, J. Mardia, M. Kubit, J. Neu, P. Griffin, M. Wootters, T. Weissman, H. Ji

This paper improves the read/write cost tradeoff in DNA-based storage by using a single LDPC code for both erasure and error correction, achieving 30-40% lower reading costs on experimental data.

bioRxiv · Sep 27, 2019 · PreprintBioengineering