B. Loll

Concerted transformation of a hyper-paused transcription complex and its reinforcing protein

This paper reveals how RfaH activates virulence gene expression by transforming its structure and stabilizing paused transcription complexes through interactions with ops hairpins.

Gene amplifications cause high-level resistance against albicidin in Gram-negative bacteria

This study identifies gene amplification as a mechanism conferring high-level resistance to albicidin in Gram-negative bacteria, validated across multiple species.

Water network in the binding pocket of fluorinated BPTI-Trypsin complexes - insights from simulation and experiment

The paper investigates how fluorination of amino acid side chains in BPTI affects inhibitor strength by analyzing water networks in the binding pocket using simulations and experiments.

Molecular Basis of Antibiotic Self-Resistance in a Bee Larvae Pathogen

The paper identifies PamZ as a self-resistance factor in Paenibacillus larvae that deactivates paenilamicin by N-acetylation and elucidates its crystal structure.

The superior salinity tolerance of wheat cultivar Shanrong No. 3 cannot be attributed to elevated Ta-sro1 poly(ADP-ribose) polymerase activity

This study investigates the molecular basis of salt tolerance in wheat cultivar SR3, finding that elevated Ta-sro1 PARP activity does not underlie its superior salinity tolerance.

Rapid high-resolution structure analysis of small, biotechnologically relevant enzymes by cryo-electron microscopy

This study demonstrates that cryo-EM can achieve high-resolution structures of small plant enzymes, enabling faster development of biocatalysts for terpenes and terpenoids.