Author

T. Dang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 2 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 10 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

B. Ladoux· 2 shared C. Wang· 2 shared G. Sankara· 2 shared R.-M. Mege· 2 shared A. A. Joshi· 1 shared A. Bhushan· 1 shared A. C. Wang· 1 shared A. Doostmohammadi· 1 shared

Activity by Year

2019-2022 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

B. Ladoux

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Directed Biosynthesis of Mitragynine Stereoisomers

C. Schotte, Y. Jiang, D. Grzech, T. Dang, L. Laforest, F. Leon, M. Mottinelli, S. S. Nadakuduti, C. R. McCurdy, S. E. O'Connor

This study identifies the biosynthetic pathway for mitragynine and related alkaloids and uses it to enzymatically produce mitragynine, its epimer, and fluorinated analogues.

bioRxiv · Dec 22, 2022Biochemistry

The Arabidopsis INNER NO OUTER (INO) gene acts exclusively and quantitatively in regulation of ovule outer integument development

C. S. Gasser, D. J. Skinner, T. Dang

This study shows that the INO gene quantitatively regulates outer integument development in Arabidopsis ovules through its protein activity levels.

bioRxiv · Aug 12, 2022Plant Biology

A small H2O-soluble ingredient of royal jelly lower cholesterol levels in liver cells by suppressing squalene epoxidase

C. Wang, Z.-y. Jiang, J. Wang, J.-x. Lou, Y.-y. Nian, X. L. Liu, T. Dang, X.-m. Meng

This study identifies a water-soluble fraction of royal jelly that reduces squalene epoxidase expression in liver cells, thereby lowering cholesterol levels.

bioRxiv · Jun 14, 2022Cell Biology

Molecular Basis of Antibiotic Self-Resistance in a Bee Larvae Pathogen

T. Dang, B. Loll, S. Müller, R. Skobalj, J. Ebeling, T. Bulatov, S. Gensel, J. Göbel, M. Wahl, E. Genersch, A. Mainz, R. D. Süssmuth

The paper identifies PamZ as a self-resistance factor in Paenibacillus larvae that deactivates paenilamicin by N-acetylation and elucidates its crystal structure.

Nature Communications · Apr 29, 2022Peer-reviewedBiochemistry

Arbuscular mycorrhizal fungal composition across US citrus orchards, management strategies, and disease severity spectrum

M. Xi, E. Deyett, N. Ginnan, V. E. T. M. Ashworth, T. Dang, S. Bodaghi, G. Vidalakis, M. C. Roper, S. Glassman, P. Rolshausen

The paper assesses how geographical location, management strategies, and disease severity affect arbuscular mycorrhizal fungal communities in citrus root systems across US orchards.

bioRxiv · Mar 1, 2022 · PreprintMicrobiology

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

D. D. Shi, M. R. Savani, M. M. Levitt, A. C. Wang, J. E. Endress, C. E. Bird, J. Buehler, S. A. Stopka, M. S. Regan, Y.-F. Lin, W. Gao, J. Khanal, M. Xu, B. Huang, R. B. Jennings, , McBray

This study identifies de novo pyrimidine synthesis as a therapeutic target in IDH mutant gliomas, showing that DHODH inhibitors are effective in preclinical models.

bioRxiv · Nov 30, 2021Cancer Biology

Nature of active forces in tissues: how contractile cells can form extensile monolayers

L. Balasubramaniam, A. Doostmohammadi, T. B. Saw, G. Sankara, R. Mueller, T. Dang, M. Thomas, S. Gupta, S. Sonam, A. S. Yap, Y. Toyama, R.-M. Mege, J. Yeomans, B. Ladoux

The paper investigates how epithelial cell monolayers switch from extensile to contractile behavior as intercellular contacts weaken, revealing mechanotransductive responses and implications for cell sorting and tissue dynamics.

bioRxiv · Oct 28, 2020Biophysics

Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium

L. E. Carter, D. P. Cook, C. W. McCloskey, T. Dang, O. Collins, L. F. Gamwell, H. A. Dempster, B. C. Vanderhyden

This study investigates stemness traits in ovarian surface epithelium and finds that stemness is context-specific and not consistently linked to specific signaling pathways or a single population.

bioRxiv · Jun 10, 2020Cell Biology

A Novel Standalone Microfluidic Device for Local Control of Oxygen Tension for Intestinal-Bacteria Interactions

C. Wang, T. Dang, J. Baste, A. A. Joshi, A. Bhushan

This paper introduces a microfluidic device that creates a dual-oxygen environment for studying intestinal epithelial and bacterial interactions without external chambers.

bioRxiv · May 22, 2020Bioengineering

Myosin II isoforms play distinct roles in adherens junction biogenesis

B. Ladoux, R.-M. Mege, T. Dang, M. Heuze, J. Van Hest, G. Sankara, P. Marcq, J. D'Alessandro, V. Cellerin, D. S. Williams

This study identifies distinct roles of myosin II isoforms in adherens junction biogenesis, showing NMIIA provides mechanical force for junction maintenance while NMIIB facilitates E-cadherin clustering and anisotropic stress.

bioRxiv · Mar 16, 2019Cell Biology