DRP1-mediated mitochondrial fission is essential to maintain cristae morphology and bioenergetics
G. L. Robertson, S. N. Riffle, M. Patel, A. Marshall, H. Beasley, E. Garza-Lopez, J. Shao, Z. Vue, M. S. Stoll, S. de Wet, R. P. Theart, B. Loos, A. Hinton, J. A. Mears, V. Gama
This study investigates how DRP1 mutations affect mitochondrial and peroxisomal dynamics, leading to metabolic dysfunction and structural abnormalities in EMPF1 patient fibroblasts.
bioRxiv · Dec 31, 2021Cell Biology