Author

B. Lucendo Villarin

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Biochemistry· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. J. Drake· 1 shared A. Thakker· 1 shared C. Ludwig· 1 shared D. A. Tennant· 1 shared D. C. Hay· 1 shared G. G. Lavery· 1 shared J. Meseguer Ripolles· 1 shared J. P. Thomson· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. J. Drake

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1 paper

Recent·Most cited

BiochemistrybioRxivJun 23, 2020

Macrovesicular steatosis in nonalcoholic fatty liver disease is a consequence of purine nucleotide cycle driven fumarate accumulation

M. C. Sinton, B. Lucendo Villarin, J. Meseguer Ripolles…·A. J. Drake

This study identifies fumarate accumulation driven by purine nucleotide cycle activity as a cause of macrovesicular steatosis in NAFLD using human pluripotent stem cell-derived hepatocytes.

DOI 10.1016/j.isci.2020.101931

humanbulk RNA-seq

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