Author

B. M. Ryan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Ruppin· 3 shared S. Sinha· 3 shared A. A. Schäffer· 2 shared A. Zingone· 2 shared J. S. Lee· 2 shared A. Deshpande· 1 shared A. Erez· 1 shared C. Xing· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

E. Ruppin

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Author profile →

4 papers

Recent·Most cited

Sex biases in cancer and autoimmune disease incidence are strongly positively correlated with mitochondrial gene expression across human tissues

D. R. Crawford, S. Sinha, N. U. Nair, B. M. Ryan, J. S. Barnholtz-Sloan, S. M. Mount, A. Erez, K. Aldape, P. E. Castle, P. S. Rajagopal, C.-P. Day, A. A. Schäffer, E. Ruppin

bioRxiv · Sep 7, 2021Cancer Biology

NNAL, a major metabolite of tobacco-specific carcinogen NNK, promotes lung cancer progression through deactivating LKB1 in an isomer-dependent manner

T. Bian, Y. Wang, J. F. Botello, Q. Hu, Y. Jiang, A. Zingone, P. A. Corral, F. Z. Aly, Y. Wu, B. M. Ryan, L. Jin, C. Xing

This study shows that (R)-NNAL promotes lung cancer progression by deactivating LKB1 through β-AR signaling, while (S)-NNAL has weaker effects.

bioRxiv · Jun 15, 2021 · PreprintCancer Biology

Integrated computational and experimental identification of p53, KRAS and VHL mutant selection associated with CRISPR-Cas9 editing

S. Sinha, K. O. Barbosa, K. Cheng, M. D. Leiserson, D. M. Wilson, B. M. Ryan, Z. A. Ronai, J. S. Lee, A. Deshpande, E. Ruppin

The paper identifies p53, KRAS, and VHL mutations as being selected during CRISPR-Cas9 editing through computational and experimental analysis.

bioRxiv · Nov 2, 2019 · PreprintCancer Biology

Higher prevalence of homologous recombination-deficiency in lung squamous carcinoma from African Americans

S. Sinha, B. M. Ryan, E. Ruppin, J. S. Lee, K. A. Mitchell, A. Zingone, N. Sinha, A. A. Schäffer, E. Bowman

The paper compares genomic features between African American and European American lung cancers, finding higher genomic instability and homologous recombination-deficiency in African American tumors.

bioRxiv · May 27, 2019 · PreprintCancer Biology