Author

B. Markelc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Kaeppler· 3 shared R. J. Muschel· 2 shared A. Beardo· 1 shared A. J. Groot· 1 shared A. L. Harris· 1 shared A. Miar· 1 shared H. Byrne· 1 shared H. M. Byrne· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

J. Kaeppler

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3 papers

Recent·Most cited

Abnormal morphology biases haematocrit distribution in tumour vasculature and contributes to heterogeneity in tissue oxygenation

M. O. Bernabeu, J. Kory, J. A. Grogan, B. Markelc, A. Beardo, M. d'Avezac, R. Enjalbert, J. Kaeppler, N. Daly, J. Hetherington, T. Krueger, P. K. Maini, J. M. Pitt-Francis, R. J. Muschel, T. Alarcon, H. M. Byrne

The paper investigates how abnormal vascular morphology affects haematocrit distribution and tissue oxygenation in tumours, introducing a metric λ to monitor anti-angiogenic treatment efficacy.

bioRxiv · Aug 28, 2020 · PreprintCancer Biology

A lineage-tracing tool to map the fate of hypoxic tumour cells

J. A. F. Vermeer, J. Ient, B. Markelc, J. Kaeppler, L. M. O. Barbeau, A. J. Groot, R. J. Muschel, M. A. Vooijs

This paper develops a lineage-tracing tool to study hypoxic tumour cell behaviour in vivo, showing post-hypoxic cells are more proliferative.

bioRxiv · Mar 3, 2020Cancer Biology

Radiation resistant cancer cells enhance the survival and resistance of sensitive cells in prostate spheroids

P. Kannan, M. Paczkowski, A. Miar, J. Owen, W. W. Kretzschmar, S. Lucotti, J. Kaeppler, J. Chen, B. Markelc, L. A. Kunz-Schughart, A. L. Harris, M. Partridge, H. Byrne

This study shows radiation-resistant prostate cancer cells enhance survival and resistance of sensitive cells in spheroids through competitive and antagonistic interactions.

bioRxiv · Mar 3, 2019 · PreprintCancer Biology