Author

B. Orcutt-Jahns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. S. Meyer· 2 shared A. C. Weiner· 1 shared A. M. Farhat· 1 shared C. Posner· 1 shared C. Tan· 1 shared S. M. Carlson· 1 shared Z. S. Kim· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

A. S. Meyer

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2 papers

Recent·Most cited

BioengineeringbioRxivNov 25, 2020

A quantitative view of strategies to engineer cell-selective ligand binding

C. Tan, B. Orcutt-Jahns, A. S. Meyer

This paper develops a quantitative model to evaluate strategies for enhancing cell-selective ligand binding through affinity, valency, and multi-ligand approaches.

DOI 10.1093/intbio/zyab019

statistical modeldrug response / drug discovery

𝕏 PostBluesky

ImmunologybioRxivMar 19, 2020

Modeling Cell-Specific Dynamics and Regulation of the Common Gamma Chain Cytokines

A. M. Farhat, A. C. Weiner, C. Posner…·A. S. Meyer

The paper builds a dynamical model of common gamma-chain cytokines to predict ligand responses and shows receptor trafficking and tensor factorization are essential for accurate modeling and engineering cell-specific responses.

DOI 10.1016/j.celrep.2021.109044

humanproteomics

𝕏 PostBluesky