Nano-Emulsion Adjuvant Enhances Cross-presentation by Lipid Body Formation Independent of Glycolysis
M. Suresh, W. Lee, B. Kingstad-Bakke, B. Paulson, A. Larsen, K. Overmyer, C. Marinaik, K. Dull, R. Toy, G. Vogel, K. Mueller, K. Tweed, A. Walsh, J. Russell, K. Saha, , K. Roy
This study shows that the nano-emulsion adjuvant Adjuplex enhances cross-presentation in dendritic cells without requiring glycolysis, relying instead on lipid body formation and ROS.
bioRxiv · May 8, 2020 · PreprintImmunology