Cancer BiologybioRxiv
Elucidation of tumor-stromal heterogeneity and the ligand-receptor interactome by single cell transcriptomics in real-world pancreatic cancer biopsies
J. J. Lee, V. Bernard, A. Semaan…·P. A. Guerrero
This study uses scRNA-seq on pancreatic cancer biopsies to characterize tumor-stromal heterogeneity and ligand-receptor interactions, showing its utility over patient-derived organoids for precision oncology.