Distinct CD8+ T Cell Programming in the Tumor Microenvironment Contributes to Sex Bias in Bladder Cancer Outcome
H. Kwon, D. Chung, S. Kaneko, A. Li, L. Zhou, B. Riesenberg, N.-J. Song, D. Sundi, X. Li, Z. Li
The paper identifies sex differences in CD8+ T cell programming in bladder cancer, showing male-biased T cell exhaustion and implications for immune checkpoint therapy.
bioRxiv · Apr 13, 2020Immunology