ImmunologybioRxivPreprint
Compartment-driven imprinting of intestinal CD4 (regulatory) T cells in inflammatory bowel disease and homeostasis
L. Lutter, J. J. M. ter Linde, E. C. Brand…·F. van Wijk
The paper examines CD4 T cell changes in inflammatory bowel disease, finding compartment-specific transcriptional programming driven by regulators like ARID4B and SATB1, with epithelial translocation dampening pro-inflammatory responses.
DOI 10.1101/2022.05.06.490870