B. Shaw

The genetic origins and impacts of historical Papuan migrations into Wallacea

This study uses genome data to show that most Papuan-related ancestry in Wallacea comes from New Guinea migrations, not from ancient human settlers.

Post-translational regulation of the Numb/Notch pathway in neurogenesis and cancer by Dlk2

This study identifies Dlk2 as a regulator of Numb/Notch pathway in zebrafish neurogenesis and human cancer, showing its role in modulating Numb phosphorylation and Notch signaling.

Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing

Single cell based high-throughput Ig and TCR repertoire sequencing analysis in rhesus macaques

This study develops and validates high-throughput single-cell immune repertoire sequencing for rhesus macaques, enabling analysis of Ig and TCR repertoires in over 60,000 cells.

Pseudogene-mediated gene conversion after CRISPR-Cas9 editing demonstrated by partial CD33 conversion with SIGLEC22P

The paper demonstrates that CRISPR-Cas9 editing can lead to pseudogene-mediated gene conversion, resulting in unexpected missense mutations in CD33 through homology repair with the SIGLEC22P pseudogene.

Recording and reproducing the diurnal oviposition rhythms of wild populations of the soft- and stone- fruit pest Drosophila suzukii

This study investigates and reproduces diurnal oviposition rhythms of Drosophila suzukii in the field and lab, showing circadian control and disruption by temperature.