R. S. Hamilton

This study identifies Dlk2 as a regulator of Numb/Notch pathway in zebrafish neurogenesis and human cancer, showing its role in modulating Numb phosphorylation and Notch signaling.

This study shows that maternal group 2 innate lymphoid cells (ILC2s) support fetal growth and prevent endotoxin-induced abortion in mice by modulating immune responses and placental function.

The paper shows that implants stiffer than host tissue trigger a foreign body reaction via mechanosensing, and soft coatings reduce inflammation and fibrosis.

The paper identifies placental erythro-myeloid progenitors (PEMPs) that generate Hofbauer cells, showing human primitive haematopoiesis occurs in the placenta, not just the yolk sac.

The paper characterizes first trimester human placental macrophages, identifying Hofbauer cells as HLA-DR-FOLR2+ macrophages with microbicidal properties and secreted factors influencing placental angiogenesis.

This study identifies placental hormones associated with pregnancy complications by analyzing the secretome of mouse placental cells and linking findings to human pregnancy outcomes.