B. Shit

IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission

This study shows that immune priming in Drosophila enhances survival and reduces pathogen transmission by requiring the IMD pathway and Diptericin-B.

Correlated responses to experimental evolution of increased post-infection survival in Drosophila melanogaster: Life-history trade-offs and reaction to novel stressors

This study shows that Drosophila melanogaster can rapidly evolve increased resistance to E. faecalis infection without life-history costs or abiotic stress resistance.

Ageing leads to nonspecific antimicrobial peptide responses in Drosophila melanogaster

This study shows that ageing in Drosophila melanogaster reduces the specificity of antimicrobial peptide (AMP) responses, requiring multiple AMPs for survival, while young flies can resist infections with single AMPs.

Effect of larval diet on adult immune function is contingent upon selection history and host sex in Drosophila melanogaster

This study shows that Drosophila melanogaster adapted to bacterial infections maintain better immune function under poor diets, with sex-dependent effects.

Recurrent evolution of cross-resistance in response to selection for improved post-infection survival in Drosophila melanogaster

This study shows that selecting Drosophila melanogaster for resistance to one bacterial pathogen leads to generalized cross-resistance against other pathogens.

Mating enhances immune function of Drosophila melanogaster populations against bacterial pathogens

This study finds that mating in Drosophila melanogaster enhances population survival against bacterial infections, with no sexual dimorphism in immune response.