Author

B. Sridharan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Biankin· 1 shared A. Cheng· 1 shared A. Gehman· 1 shared C. V. Leiton· 1 shared C.-H. Pan· 1 shared D. K. Chang· 1 shared D. Poore· 1 shared E. Kim· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Biankin

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2 papers

Recent·Most cited

Lung Tumor Microphysiological System with 3D Endothelium to Evaluate Modulators of T-Cell Infiltration

K. M. Wisdom, J. Suijker, L. van den Broek, B. Sridharan, T. S. P. Grandhi, A. Cheng, M. Lamb, S. A. Titus, A. Gehman, D. Poore, N. Shah, S.-H. Cheng, E. Kim, S. Griffin, J. Ekert

This paper introduces a 3D lung tumor on chip model with endothelium to evaluate T-cell infiltration modulators and demonstrates its utility in assessing immune chemotaxis and vascular responses.

bioRxiv · Aug 3, 2022 · PreprintBioengineering

An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer

C.-H. Pan, Y. Otsuka, B. Sridharan, M. Woo, S. Babu, C. V. Leiton, J. D. Bai, D. K. Chang, A. Biankin, L. Scampavia, T. Spicer, L. F. Escobar-Hoyos, K. R. Shroyer

This study identifies K17 as a biomarker for PDAC and shows that PPT, a microtubule inhibitor, is more effective against K17-expressing PDAC cells when combined with Gemcitabine.

bioRxiv · Oct 11, 2019Cancer Biology