Lung Tumor Microphysiological System with 3D Endothelium to Evaluate Modulators of T-Cell Infiltration
K. M. Wisdom, J. Suijker, L. van den Broek, B. Sridharan, T. S. P. Grandhi, A. Cheng, M. Lamb, S. A. Titus, A. Gehman, D. Poore, N. Shah, S.-H. Cheng, E. Kim, S. Griffin, J. Ekert
This paper introduces a 3D lung tumor on chip model with endothelium to evaluate T-cell infiltration modulators and demonstrates its utility in assessing immune chemotaxis and vascular responses.
bioRxiv · Aug 3, 2022 · PreprintBioengineering