TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
E. Demirdizen, R. Al-Ali, A. Narayanan, X. Sun, J. P. Varga, B. Steffl, M. Brom, D. Krunic, C. Schmidt, G. Schmidt, F. Bestvater, J. Taranda, S. Turcan
This study identifies TRIM67 as an oncogene in oligodendrogliomas that promotes cell motility, tumor growth, and membrane blebbing through Rho GTPase/ROCK signaling.
bioRxiv · Nov 5, 2021Cancer Biology