Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
M. S. Egan, E. A. O'Rourke, S. K. Mageswaran, B. Zuo, I. Martynyuk, T. Demissie, E. N. Hunter, A. R. Bass, Y.-W. Chang, I. E. Brodsky, S. Shin
This study identifies caspase-1 and GSDMD as key mediators of inflammasome responses that restrict Salmonella replication in human macrophages.
bioRxiv · Jul 17, 2023Microbiology