NeurosciencebioRxivPreprint
Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug
Sara Faccidomo, Briana L. Saunders, Ashley M. May…·Clyde W. Hodge
This study shows that ethanol self-administration increases GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens, which enhances ethanol's reinforcing effects through an NSF-dependent mechanism.