Clyde W. Hodge

This study investigates the separate roles of CRF and GABA release from BNSTCRF neurons in ethanol self-administration in mice, finding CRF deletion reduces ethanol intake while GABA suppression affects motivation differently in males and females.

This study shows that TARP γ-8 regulates ethanol reinforcement and relapse in mice, with reduced self-administration and cue-induced reinstatement in TARP γ-8 heterozygous null mice.

This study examines sex differences in ethanol consumption and its regulation by glutamate AMPA receptors in C57BL/6J mice, finding higher ethanol intake and reinforcement in females.

This study shows that ethanol self-administration increases GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens, which enhances ethanol's reinforcing effects through an NSF-dependent mechanism.

This study inhibits TARP γ-8 bound AMPARs in specific brain regions to show their role in alcohol and sucrose reinforcement, finding region-specific effects on reward behavior.

This study shows that calcium-permeable AMPA receptors and GluA1 trafficking in the basolateral amygdala regulate alcohol reinforcement in mice.

This study shows that neurotensin neurons in the central amygdala of mice influence ethanol and sweet fluid consumption through projections to the parabrachial nucleus.

This study shows that non-dependent alcohol drinking worsens AD-like neural and behavioral issues in 3xTg-AD mice.