ImmunologybioRxiv
Duox activation in Drosophila Malpighian tubules stimulates intestinal epithelial renewal through a countercurrent flow
Zhonggeng Liu, Hongyu Zhang, Bruno Lemaitre, Xiaoxue Li
The paper shows Duox in Drosophila Malpighian tubules produces ROS that trigger Upd3 release, which then stimulates gut epithelial renewal via a countercurrent flow system.
DOI 10.1016/j.celrep.2024.114109