Author

C. A. Devlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Organism:human· 3 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. Procko· 4 shared A. C. McShan· 2 shared D. Moschidi· 2 shared N. G. Sgourakis· 2 shared A. Aguhob· 1 shared A. B. Malik· 1 shared B. Selvam· 1 shared D. Flores-Solis· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersImmunology

E. Procko

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An engineered ACE2 decoy receptor can be administered by inhalation and potently targets the BA.1 and BA.2 omicron variants of SARS-CoV-2

L. Zhang, K. K. Narayanan, L. Cooper, K. K. Chan, C. A. Devlin, A. Aguhob, K. Shirley, L. Rong, J. Rehman, A. B. Malik, E. Procko

bioRxiv · Mar 28, 2022 · PreprintMicrobiology

Deep Mutagenesis of a Transporter for Uptake of a Non-Native Substrate Identifies Conformationally Dynamic Regions

H. J. Ellis, M. Chan, B. Selvam, E. Walter, C. A. Devlin, S. K. Szymanski, L. K. Henry, D. Shukla, E. Procko

This study uses deep mutagenesis to identify mutations enhancing APP+ import by SERT, revealing conformational dynamics and mutationally tolerant regions along the permeation pathway.

bioRxiv · Apr 19, 2021 · PreprintBiochemistry

TAPBPR Promotes Antigen Loading on MHC-I Molecules Using a Peptide Trap

A. C. McShan, C. A. Devlin, G. I. Morozov, S. Overall, D. Moschidi, N. Akella, E. Procko, N. G. Sgourakis

This study identifies the role of TAPBPR's 16-residue loop in promoting peptide loading on MHC-I by acting as a kinetic trap, not by competing with incoming peptides.

bioRxiv · Apr 24, 2020Immunology

Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection

A. C. McShan, C. A. Devlin, S. A. Overall, J. Park, J. S. Toor, D. Moschidi, D. Flores-Solis, H. Choi, S. Tripathi, E. Procko, N. G. Sgourakis

This paper identifies molecular determinants of TAPBPR chaperone interactions with MHC-I molecules, showing that conformational dynamics and disulfide bonds influence recognition and antigen repertoire selection.

bioRxiv · Sep 24, 2019Immunology