ImmunologybioRxiv
Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection
A. C. McShan, C. A. Devlin, S. A. Overall…·N. G. Sgourakis
This paper identifies molecular determinants of TAPBPR chaperone interactions with MHC-I molecules, showing that conformational dynamics and disulfide bonds influence recognition and antigen repertoire selection.
DOI 10.1073/pnas.1915562116