C. A. Flores

This study shows that inhibiting SLC4A4, a sodium-dependent bicarbonate cotransporter, in airway epithelial cells causes a CF-like phenotype with mucus accumulation and reduced mucociliary clearance.

This study shows tamoxifen reduces neutrophil infiltration in inflamed airways across multiple mouse models without affecting mucociliary clearance.

This study shows that inhibiting KCa3.1 improves mucociliary clearance in a mouse model of muco-obstructive lung disease.

The paper revises the kinetic properties of MCT4, showing it has high lactate affinity and can extrude lactate in high-lactate environments, challenging previous pH probe-based estimates.