ImmunologybioRxivPreprint
Leishmania amazonensis infection induces PD-L1 expression on dendritic cells in an mTor-dependent manner and impairs Th1 responses in vitro and in vivo
H. L. de Matos Guedes, A. M. da Fonseca-Martins, Y. Liang…·L. Soong
This study shows that Leishmania amazonensis infection increases PD-L1 on dendritic cells via mTOR, leading to impaired Th1 responses and promoting lesion resolution.
DOI 10.1101/2022.02.15.480617