Author

C. A. Sedore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:behavioral assay· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. C. Phillips· 4 shared A. L. Coleman-Hulbert· 3 shared B. Onken· 3 shared D. Hall· 3 shared E. Chen· 3 shared E. Johnson· 3 shared G. Harinath· 3 shared G. J. Lithgow· 3 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersPhysiology

P. C. Phillips

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Author profile →

4 papers

Recent·Most cited

Transcriptomic sexual conflict at two evolutionary timescales revealed by experimental evolution in Caenorhabditis elegans

K. R. Kasimatis, J. H. Willis, C. A. Sedore, P. C. Phillips

This study uses experimental evolution in C. elegans to show sex-specific gene expression changes driven by sexual selection, revealing transcriptomic sexual conflict over short evolutionary timescales.

bioRxiv · Aug 9, 2023 · PreprintEvolutionary Biology

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

S. A. Banse, E. G. Jackson, C. A. Sedore, B. Onken, D. Hall, A. L. Coleman-Hulbert, P. Huynh, T. Garrett, E. Johnson, G. Harinath, D. Inman, S. Guo, M. Morshead, J. Xue, R. Falkowski, , P. C. Phillips

This study evaluates how compound interventions and genetic background affect healthspan and lifespan in C. elegans under stress conditions.

bioRxiv · Jan 15, 2022Physiology

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

S. A. Banse, C. A. Sedore, E. Johnson, A. L. Coleman-Hulbert, B. Onken, D. Hall, E. G. Jackson, P. Huynh, A. C. Foulger, S. Guo, T. Garrett, J. Xue, D. Inman, M. L. Morshead, W. T. Plummer, , P. C. Phillips

This study evaluates the lifespan and health effects of five compounds in Caenorhabditis nematodes, finding species- and strain-specific responses, assay-dependent outcomes, and uncoupling of lifespan and health effects.

bioRxiv · Nov 9, 2021Physiology

Automated Lifespan Determination Across Caenorhabditis Strains and Species Reveals Assay-Specific Effects of Chemical Interventions

S. A. Banse, M. Lucanic, C. A. Sedore, A. L. Coleman-Hulbert, W. T. Plummer, E. Chen, J. L. Kish, D. Hall, B. Onken, M. P. Presley, E. G. Jones, B. W. Blue, T. Garrett, M. Abbott, J. Xue, , P. C. Phillips

The paper compares manual and automated lifespan assays in Caenorhabditis strains, finding that automated methods reproduce results but show assay-specific effects of chemical interventions.

bioRxiv · Sep 14, 2019Physiology