D. Hall

Species wide inventory of Arabidopsis thaliana organellar variation reveals ample phenotypic variation for photosynthetic performance

The paper identifies organellar genetic variation in Arabidopsis thaliana and shows its impact on photosynthesis through cybrid analysis and high-throughput phenotyping.

Serial "deep-sampling" PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected hosts and allows accurate monitoring of parasite load following treatment

This study introduces deep-sampling PCR to detect and quantify T. cruzi parasite load in chronically infected hosts, revealing large variations in parasite levels and enabling treatment monitoring.

Phylochemical mapping of natural products onto the plant tree of life using text mining and large language models.

This paper maps natural products onto the plant tree of life using text mining and large language models, revealing lineage-specific distributions and demonstrating automation potential.

Equations describing semi-confluent cell growth (I) Analytical approximations

The paper presents analytical differential equations to model cell growth in 2D and 3D cultures, accounting for contact inhibition and other factors like geometry and nutrient depletion.

Scots pine - panmixia and the elusive signal of genetic adaptation

This study analyzes genetic diversity and adaptation in Scots pine across Eurasia, finding high genetic uniformity and limited signals of adaptation.

Exogenous TGFβ1 and its mimic HpTGM attenuate the heart's inflammatory response to ischaemic injury and improve long term cardiac outcomes

This study shows that exogenous TGFβ1 and its mimic HpTGM reduce inflammation and infarct size after myocardial infarction, improving cardiac outcomes.

MIL Cell: A tool for multi-scale simulation of yeast replication and prion transmission.

The paper introduces MIL-CELL, a computational tool for simulating yeast prion replication and transmission across multiple scales.

Plethora of QTLs found in Arabidopsis thaliana reveals complexity of genetic variation for photosynthesis in dynamic light conditions

The study identifies 15 QTLs associated with photoprotection in Arabidopsis thaliana under dynamic light conditions, revealing intraspecific genetic variation for photosynthetic efficiency.

Cardiac MAO-A inhibition protects against catecholamine-induced ventricular arrhythmias via enhanced diastolic calcium control

This study shows that inhibiting MAO-A in cardiomyocytes reduces arrhythmias by improving diastolic calcium control following catecholamine stress.

ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

This study shows that OPA1 deficiency in skeletal muscle increases MERC formation via ATF4, affecting calcium exchange and mitochondrial-ER tethering.

The structure, binding, and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3

This paper defines the RBPJ-interacting domain of L3MBTL3 and reports the crystal structure of the RBPJ-L3MBTL3-DNA complex, revealing molecular interactions and functional consequences of mutations.

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

This study evaluates how compound interventions and genetic background affect healthspan and lifespan in C. elegans under stress conditions.

Antioxidants green tea extract and nordihydroguaiaretic acid confer species and strain specific lifespan and health effects in Caenorhabditis nematodes

This study evaluates the lifespan and health effects of five compounds in Caenorhabditis nematodes, finding species- and strain-specific responses, assay-dependent outcomes, and uncoupling of lifespan and health effects.

The Induction of Pyrenoid Synthesis by Hyperoxia and its Implications for the Natural Diversity of Photosynthetic Responses in Chlamydomonas

This study shows that hyperoxia induces pyrenoid formation in Chlamydomonas reinhardtii, suggesting H2O2 as a signaling molecule and linking it to genetic variation in hyperoxia tolerance and pyrenoid morphology.

GLI3 Processing by the Primary Cilium Regulates Muscle Stem Cell Entry into GAlert

This study shows that GLI3 processing by primary cilia maintains satellite cell dormancy and that its absence leads to premature activation and enhanced regenerative capacity.

Assessing the effect of insecticide-treated cattle on tsetse abundance and trypanosome transmission at the wildlife-livestock interface in Serengeti, Tanzania

This study assesses the impact of farmer-led insecticide-treated cattle on tsetse fly abundance and trypanosome transmission at the wildlife-livestock interface in Serengeti, Tanzania, finding increased tsetse mortality and reduced trypanosome prevalence.

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

This study uses live-cell 3D single-molecule tracking to show that the NuRD complex decompacts chromatin and alters enhancer dynamics by increasing their movement and reducing time in a fast-diffusing state.

Automated Lifespan Determination Across Caenorhabditis Strains and Species Reveals Assay-Specific Effects of Chemical Interventions

The paper compares manual and automated lifespan assays in Caenorhabditis strains, finding that automated methods reproduce results but show assay-specific effects of chemical interventions.

Experimental evidence of invasion facilitation in the zebra mussel-killer shrimp system

The paper tests if zebra mussels facilitate killer shrimp establishment through substrate and chemical cues, finding attraction to mussel substrates and scents but no learned behavior.