Author

B. da Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Wurdak· 3 shared S. C. Short· 3 shared A. Droop· 2 shared E. S. Polson· 2 shared J. Williams· 2 shared R. K. Mathew· 2 shared A. J. Davies· 1 shared A. P. Droop· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

H. Wurdak

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Author profile →

3 papers

Recent·Most cited

A high-content screen profiles cytotoxic microRNAs in pediatric and adult glioblastoma cells and identifies miR-1300 as a potent inducer of cytokinesis failure

M. Boissinot, H. King, M. Adams, J. Higgins, T. A. Ward, L. P. Steele, D. Tams, R. Morton, E. Polson, B. da Silva, A. P. Droop, J. L. Hayes, H. Martin, P. Laslo, E. E. Morrison, , S. C. Short

This study identifies miR-1300 as a potent cytotoxic microRNA in glioblastoma cells, causing cytokinesis failure and apoptosis, with potential therapeutic applications.

bioRxiv · Oct 1, 2019 · PreprintCancer Biology

Chemically-induced Neurite-like Outgrowth Reveals Multicellular Network Function in Patient-derived Glioblastoma Cells

B. da Silva, E. S. Polson, A. Droop, R. K. Mathew, L. F. Stead, J. Williams, S. C. Short, M. Scarcia, G. Mavria, H. Wurdak

The paper shows that ROCKi promotes neurite-like outgrowth in GBM cells, forming radiation-resistant multicellular networks that can be reversed.

bioRxiv · Nov 10, 2018Cancer Biology

The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1

E. S. Polson, V. B. Kuchler, C. Abbosh, E. M. Ross, R. K. Mathew, H. A. Beard, E. Chuntharpursat-Bon, J. Williams, B. Da Silva, H. Shao, A. Patel, A. J. Davies, A. Droop, H. B. S. Griffiths, P. Chumas, , H. Wurdak

The paper shows KHS101 inhibits HSPD1 in glioblastoma cells, causing metabolic dysfunction and tumor growth reduction without affecting normal cells.

bioRxiv · Oct 18, 2017Cancer Biology