Author

C. Arnold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Lin· 1 shared A. M. Crawley· 1 shared A. Nitsche· 1 shared A. Pickering· 1 shared B. F. Arnold· 1 shared B. I. Wilkinson· 1 shared C. A. Piccirillo· 1 shared C. L. Cooper· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Lin

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Multi-variate statistical and machine learning reveals the interplay between sex and age in antibody responses to de novo SARS-CoV-2 infection and vaccination

M. Cuperlovic-Culf, S. Bennett, Y. Galipeau, P. S. McCluskie, C. Arnold, S. Bagheri, C. L. Cooper, M.-A. Langlois, J. Fritz, C. A. Piccirillo, A. M. Crawley

The paper uses statistical and machine learning methods to analyze how sex and age influence antibody responses to SARS-CoV-2 infection and vaccination.

bioRxiv · Dec 5, 2023Immunology

Image-based patch selection for deep learning to improve automated Gleason grading in histopathological slides

W. Speier, J. Li, W. Li, K. Sarma, C. Arnold

This paper improves automated Gleason grading by using image-based patch selection to enhance segmentation accuracy in histopathological slides.

bioRxiv · Sep 26, 2020 · PreprintBioengineering

Refactoring the formicamycin biosynthetic gene cluster to make high-level producing strains and new molecules

R. Devine, H. McDonald, Z. Qin, C. Arnold, K. Noble, G. Chandra, B. I. Wilkinson, M. I. Hutchings

This paper refactors the formicamycin biosynthetic gene cluster to enhance production and generate new molecules by manipulating regulatory elements.

bioRxiv · Sep 15, 2020 · PreprintMicrobiology

Can individual and integrated water, sanitation, and handwashing interventions reduce fecal contamination in the household environment? Evidence from the WASH Benefits cluster-randomized trial in rural Kenya

A. Pickering, J. Swarthout, M. Mureithi, J. Mboya, B. F. Arnold, M. Wolfe, H. Dentz, A. Lin, C. Arnold, G. Rao, C. Stewart, P. K. Ram, T. Clasen, J. Colford, C. Null

This study evaluates the effectiveness of water, sanitation, and handwashing interventions in reducing fecal contamination in rural Kenyan households, finding limited success in reducing E. coli on child hands and toys.

bioRxiv · Aug 12, 2019 · PreprintMicrobiology

XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures

K. Ellwanger, C. Arnold, S. Briese, I. Kienes, J. Pfannstiel, T. A. Kufer

This study shows that XIAP prevents RIPK2 from forming insoluble complexes, which is necessary for NOD1-dependent NF-κB activation.

bioRxiv · Feb 8, 2019Immunology

Alzheimer related genes show accelerated evolution

A. Nitsche, K. Reiche, U. Ueberham, C. Arnold, J. Hackermueller, F. Horn, P. F. Stadler, T. Arendt

The paper shows Alzheimer's disease-associated genes evolve faster than the genome, suggesting recent adaptive evolution in the human brain may influence disease mechanisms.

bioRxiv · Mar 7, 2017Evolutionary Biology