BiochemistrybioRxivPreprint
A biosensor to gauge protein homeostasis resilience differences in the nucleus compared to cytosol of mammalian cells
C. B. Raeburn, A. R. Ormsby, N. S. Moily…·D. M. Hatters
The paper develops a biosensor to compare protein homeostasis resilience in the nucleus and cytosol of human cells, finding the nucleus has lower chaperone activity and aggregation suppression capacity.
DOI 10.1101/2021.04.19.440383