Author

C. Barin-Le Guellec

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Assay:structural biology· 2 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Janaszkiewicz· 2 shared A. Toth· 2 shared F. Di Meo· 2 shared P. Marquet· 2 shared Q. Faucher· 2 shared B. Chantemargue· 1 shared H. Arnion· 1 shared M. Martin· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Janaszkiewicz

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2 papers

Recent·Most cited

Pharmacology & ToxicologyBiomedicine & PharmacotherapyPeer-reviewedApr 1, 2023

Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale

A. Janaszkiewicz, A. Toth, Q. Faucher…·F. Di Meo

This study investigates the structure and function of hOAT1 using molecular dynamics simulations, identifying substrate binding sites and allosteric mechanisms involving lipid interactions.

DOI 10.1016/j.biopha.2023.114342

humanstructural biology

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Pharmacology & ToxicologyScientific ReportsPeer-reviewedApr 29, 2022

Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes

A. Janaszkiewicz, A. Toth, Q. Faucher…·F. Di Meo

This study presents the first robust model of hOAT1 in outward-facing conformation using protein-threading and MD simulations, revealing structural and functional insights into its transport mechanism.

DOI 10.1038/s41598-022-10755-2

humanstructural biology

𝕏 PostBluesky