Cell BiologybioRxiv
Carm1 regulates the speed of C/EBPa-induced transdifferentiation by a cofactor stealing mechanism
G. T. Garcia, E. Kowenz-Leutz, T. V. Tian…·T. Graf
This study shows that a C/EBP mutation accelerates B cell to macrophage transdifferentiation by altering PU.1 interactions, and that Carm1 methylation regulates this process.