Negative durotaxis: cell movement toward softer environments
A. Isomursu, K.-Y. Park, J. Hou, C. Bo, G. Shamsan, B. Fuller, J. Kasim, M. M. Mahmoodi, T. J. Lu, G. M. Genin, F. Xu, M. Lin, M. Distefano, J. Ivaska, D. J. Odde
The paper identifies negative durotaxis, where cells migrate toward softer environments, and shows that integrin adhesion and motor-clutch dynamics drive this behavior in glioblastoma and neurites.
bioRxiv · Oct 27, 2020 · PreprintBiophysics